Tag: Sex Reversal
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Sex-determining region Y proteinĀ (SRY), orĀ testis-determining factorĀ (TDF)
Sex-determining region Y protein (SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein/transcription factor) encoded by the SRY gene that is responsible for the initiation of male sex determination in therian mammals (placental mammals and marsupials). SRY is an intronless sex-determining gene on the Y chromosome. Mutations in this gene lead to a range of disorders of sex development with varying effects on an individual’s phenotype and genotype. SRY is a member of the SOX (SRY-like box)…
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DAX1
DAX1Ā (dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1) is aĀ nuclear receptorĀ protein that in humans is encoded by theĀ NR0B1Ā geneĀ (nuclear receptor subfamily 0, group B, member 1).Ā TheĀ NR0B1Ā gene is located on the short (p) arm of theĀ X chromosomeĀ between bands Xp21.3 and Xp21.2, fromĀ base pairĀ 30,082,120 to base pair 30,087,136. Function This gene encodes a protein…
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DMRT1
Doublesex and mab-3 related transcription factor 1, also known asĀ DMRT1, is aĀ proteinĀ which in humans is encoded by theĀ DMRT1Ā gene. Function DMRT1 is a dose sensitive transcription factor protein that regulatesĀ Sertoli cellsĀ and germ cells. The DMRT1 gene is located at the end of the 9th chromosome. This gene is found in a cluster with two other members…
NOTES
- š§¬ Disease Table with Low Sodium Connection
- š§ Sodium Reduction and Sodium Replacement: A History of Reformulation and Exploding Diseases, Including Many Diseases Unheard of Before Deadly Sodium Policies
- š§ The DEADLY 1500 mg Sodium Recommendation predates the WHOās formal global sodium reduction push by nearly a decade (and it’s even worse than that)
- š§¬ What Is Beta-Glucuronidase?
- When Sugar Was Salt: Crystalline Confusion and the Covenant of Sweetness
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