Tag: Tau

  • 🧬 CBP in Alzheimer’s Terrain: A Scribe Silenced by Sodium Collapse

    🔹 1. Presenilin Mutations → CBP Suppression Presenilin loss doesn’t just build plaques—it silences the terrain’s scribe. 🔹 2. Amyloid & Tau → Oxidative Siege on CBP CBP is the epigenetic quill. Aβ and tau soak it in oxidative ink. 🧂 Sodium & SCN⁝: The Forgotten Protectors of CBP 🔹 Sodium Sodium is the signal.…

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  • Protein phosphorylation was first reported in 1906

    Protein phosphorylation is a reversible post-translational modification of proteins in which an amino acid residue is phosphorylated by a protein kinase by the addition of a covalently bound phosphate group. Phosphorylation alters the structural conformation of a protein, causing it to become activated, deactivated, or otherwise modifying its function. Approximately 13,000 human proteins have sites that are phosphorylated. The reverse reaction of phosphorylation is called dephosphorylation, and is catalyzed by…

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