Tag: Testes
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ADAM36: The Reproductive Enigma
ADAM36 is the protein that’s playing a mysterious role in the world of reproduction! ADAM36 is like that enigmatic character in a novel who appears briefly but leaves a lasting impression. This protein is primarily expressed in the male reproductive system, particularly in the testis and epididymis. Picture ADAM36 as the secret agent of sperm…
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ADAM27: The Redundant Reproductive Regulator
ADAM27 is the protein that’s playing a subtle yet intriguing role in the world of reproduction! ADAM27 is like that understudy who’s always ready to step in but rarely gets called onto the stage. This protein is exclusively expressed in the testis, suggesting it’s got some reproductive business to attend to1. Picture ADAM27 as the…
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ADAM25: The Testicular Troublemaker
ADAM25 is the protein that’s making waves in the world of male reproduction! ADAM25, also known as testase 2, is like that friend who only shows up for guy’s night out. This protein is exclusively expressed in the testes, suggesting it’s got some serious business to attend to in the male reproductive system1. Picture ADAM25…
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ADAM31: The Elusive Rodent Relative
ADAM31 is the protein that’s playing hide-and-seek with human geneticists! ADAM31 is like that distant cousin who only shows up at family reunions in other countries. While it’s a well-known member of the ADAM family in mice, it’s conspicuously absent from the human genome. In mice, ADAM31 is expressed in the testis, suggesting a role…
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ADAM29: The Sperm’s Secret Weapon
ADAM29 is the protein that’s bringing a whole new meaning to “family planning”! ADAM29 is like that mysterious friend who shows up at all the important life events but keeps their day job a secret. This protein is primarily expressed in the testis, making it a VIP member of the reproductive club45. Picture ADAM29 as…
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ADAM21: The Neurological Ninja of Reproduction
ADAM21 is the protein that’s bridging the gap between your brain and your… well, let’s just say your reproductive ambitions! ADAM21 is like that friend who’s always making unexpected connections. While most ADAM proteins are content with hanging out in the reproductive organs, ADAM21 decided to take the scenic route through the nervous system. Picture…
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ADAM20 is the protein that’s all about that bass – and by bass, we mean testes
ADAM20 is the ultimate homebody of the ADAM family. While its cousins are out gallivanting all over the body, ADAM20 is exclusively expressed in the testes3. It’s like that friend who never leaves their man cave, but boy, do they know how to throw a party when you visit! This protein is so exclusive, it makes…
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ADAM18: The Sperm’s Secret Identity
ADAM18 is the protein with more aliases than a secret agent! Also known as ADAM27, this mysterious molecule is the James Bond of the sperm world. ADAM18 is the ultimate sperm surface protein, giving our little swimmers their sleek and suave exterior. It’s like the tailored tuxedo of the cellular world, ensuring sperm look their…
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Sex-determining region Y protein (SRY), or testis-determining factor (TDF)
Sex-determining region Y protein (SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein/transcription factor) encoded by the SRY gene that is responsible for the initiation of male sex determination in therian mammals (placental mammals and marsupials). SRY is an intronless sex-determining gene on the Y chromosome. Mutations in this gene lead to a range of disorders of sex development with varying effects on an individual’s phenotype and genotype. SRY is a member of the SOX (SRY-like box)…
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