Tag: Thymus
-
Omenn Syndrome: When Your Body Throws Its Own Surprise Party
Imagine your immune system as an overzealous party planner, but instead of organizing a fun bash, it’s staging a revolt against your own body. Welcome to the world of Omenn syndrome, where your T cells decide to go rogue and treat your organs like they’re uninvited guests. These rebellious T cells, armed with mutant RAG…
-
Graft-versus-host disease (GvHD) is divided into acute and chronic forms
Graft-versus-host disease (GvHD) is a syndrome, characterized by inflammation in different organs. GvHD is commonly associated with bone marrow transplants and stem cell transplants. Not to be confused with Host-versus-graft disease. White blood cells of the donor’s immune system which remain within the donated tissue (the graft) recognize the recipient (the host) as foreign (non-self). The white blood cells present within the…
-
Melanin-concentrating hormone (MCH) aka PMCH
Melanin-concentrating hormone (MCH), also known as pro-melanin stimulating hormone (PMCH), is a cyclic 19-amino acid orexigenic hypothalamicpeptide originally isolated from the pituitary gland of teleost fish, where it controls skin pigmentation. Barson JR, Morganstern I, Leibowitz SF (2013). “Complementary roles of orexin and melanin-concentrating hormone in feeding behavior”. International Journal of Endocrinology. 2013: 983964. doi:10.1155/2013/983964. PMC 3727095. PMID 23935621. In mammals it is involved in the regulation of feeding behavior, mood,…
