Tag: Thyroid
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Snake Venom: The Hormone Hijacker 🐍
Imagine a villainous mastermind that can infiltrate your body’s hormonal headquarters, manipulating the delicate balance of estrogen and other hormones. Welcome to the world of snake venom, where the stakes are high and the effects are unpredictable. Estrogen’s Uninvited Guest: When Snake Venom Crashes the Hormone Hoedown Prepare for the most bizarre gatecrasher at the…
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HFE H63D & VO2 max
SMOKE EM IF YOU GOT EM The HFE H63D is a single-nucleotide polymorphism in the HFE gene (c.187C>G, rs1799945), which results in the substitution of a histidine for an aspartic acid at amino acid position 63 of the HFE protein (p.His63Asp). HFE participates in the regulation of iron absorption. Homozygous H63D variant can occasionally be the cause of hemochromatosis. It is also…
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Dr. Leo Stanley
Let it be known throughout the land that Dr. Leo Leonidas Stanley, a man of most peculiar proclivities, did preside over San Quentin’s medical realm from the year of our Lord 1913 to 1951. This self-proclaimed surgeon, bereft of true surgical experience, did embark upon a crusade most bizarre. With a scalpel in his hand…
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Evidence of the protective effect of smoking against thyroid cancer
Cigarette smoking and the risk of thyroid cancer. Kreiger N, Parkes R. Cigarette smoking and the risk of thyroid cancer. Eur J Cancer. 2000 Oct;36(15):1969-73. doi: 10.1016/s0959-8049(00)00198-2. PMID: 11000579. Thyroid cancer risk and smoking status: a meta-analysis. Cancer Causes Control Cho YA, Kim J. Thyroid cancer risk and smoking status: a meta-analysis. Cancer Causes Control.…
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The chief cells of the parathyroid glands sense the amount of calcium in the blood, and release the calcium-increasing hormone parathyroid hormone (PTH) accordingly
Parathyroid chief cells (also called parathyroid principal cells or simply parathyroid cells) are one of the two cell types of the parathyroid glands, along with oxyphil cells. The chief cells are much more prevalent in the parathyroid gland than the oxyphil cells. It is perceived that oxyphil cells may be derived from chief cells at puberty, as they are not present at…
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Parafollicular cells aka C cells secrete calcitonin and several neuroendocrine peptides
Parafollicular cells, also called C cells, are neuroendocrine cells in the thyroid. The primary function of these cells is to secrete calcitonin. They are located adjacent to the thyroid follicles and reside in the connective tissue. These cells are large and have a pale stain compared with the follicular cells. In teleost and avian species these cells occupy a structure outside the thyroid…
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Triiodothyronine, aka T3
Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate. Bowen, R. (2010-07-24). “Physiologic Effects of Thyroid Hormones”. Colorado State University. Retrieved 2013-09-29. Production of T3 and its prohormone thyroxine (T4) is activated by thyroid-stimulating hormone (TSH), which is released from the anterior pituitary gland. This pathway is part of a closed-loop feedback process: Elevated…
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Calcitonin
Calcitonin is a 32 amino acid peptide hormone secreted by PARAFOLLICULAR CELLS (also known as C cells) of the thyroid (or endostyle) in humans and other chordates in the ultimopharyngeal body. It acts to reduce blood calcium (Ca2+), opposing the effects of PARATHYROID HORMONE (PTH). Its importance in humans has not been as well established as its importance in other animals, as its function is usually not significant in the…
NOTES
- 🧬 Disease Table with Low Sodium Connection
- 🧂 Sodium Reduction and Sodium Replacement: A History of Reformulation and Exploding Diseases, Including Many Diseases Unheard of Before Deadly Sodium Policies
- 🧂 The DEADLY 1500 mg Sodium Recommendation predates the WHO’s formal global sodium reduction push by nearly a decade (and it’s even worse than that)
- 🧬 What Is Beta-Glucuronidase?
- When Sugar Was Salt: Crystalline Confusion and the Covenant of Sweetness
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