Pharmacologically, nicotine acts on cholinergic (nicotinic-specific) receptors which are depleted in AD and PD. Nicotinic receptors also interact closely with several neurotransmitters including dopamine, which is implicated in both PD and Gilles de la Tourettes’s syndrome

Does nicotine have beneficial effects in the treatment of certain diseases? Birtwistle J, Hall K. Does nicotine have beneficial effects in the treatment of certain diseases? Br J Nurs. 1996…

Three mechanisms predominate for beneficial effects of smoking: the ‘anti-estrogenic effect’ of smoking; alterations in prostaglandin production; and stimulation of nicotinic cholinergic receptors in the central nervous system

Beneficial effects of nicotine and cigarette smoking: the real, the possible and the spurious Baron JA. Beneficial effects of nicotine and cigarette smoking: the real, the possible and the spurious.…

Smoking is beneficial against Parkinson’s, Alzheimer’s, allergic alveolitis, nausea and vomiting of pregnancy, pre-eclampsia, fibroids, carcinoma of body of uterus, ulcerative colitis, pyoderma gangrenosum, aphthous stomatitis and ulceration, pemphigus, herpes simplex and acne

Smoking can be good for you Wolf R, Orion E, Matz H, Maitra S, Rowland-Payne C. Smoking can be good for you. J Cosmet Dermatol. 2004 Apr;3(2):107-11. doi: 10.1111/j.1473-2130.2004.00069.x. PMID:…

Primary sclerosing cholangitis, like ulcerative colitis, is a disease of non-smokers as the odds of having PSC are significantly decreased among current and former smokers 

Cigarette smoking, appendectomy, and tonsillectomy as risk factors for the development of primary sclerosing cholangitis: a case control study Mitchell SA, Thyssen M, Orchard TR, Jewell DP, Fleming KA, Chapman…

Smoking cessation significantly raises risk and incidence of type-2 diabetes and obstructive pulmonary disease

Study shows increased risk of diabetes after smoking cessation lasts for 12 years Yeh HC, Duncan BB, Schmidt MI, Wang NY, Brancati FL. Smoking, smoking cessation, and risk for type…

Glucuronic acid is a uronic acid that was first isolated from urine

Glucuronic acid (from Greek ÎłÎ»Î”ῊÎșÎżÏ‚ “wine, must” and Îżáœ–ÏÎżÎœ “urine“) is a uronic acid that was first isolated from urine (hence the name”uronic acid”). It is found in many gums such as gum arabic (approx. 18%), xanthan, and kombucha tea and is important for the metabolism of…

Farnesol and Farnesene

Farnesol is a natural 15-carbon organic compound which is an acyclic sesquiterpene alcohol. Under standard conditions, it is a colorless liquid. It is hydrophobic, and thus insoluble in water, but miscible with oils. Farnesol is produced…