Tag: Toxicology
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Glycoside
In chemistry, a glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosides. These can be activated by enzyme hydrolysis, which causes the sugar part to be broken off, making the chemical available for use. Many such plant glycosides are used as medications.…
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A glucuronide, aka glucuronoside, is any substance produced by linking glucuronic acid to another substance via a glycosidic bond.
A glucuronide, also known as glucuronoside, is any substance produced by linking glucuronic acid to another substance via a glycosidic bond.[1] The glucuronides belong to the glycosides. Glucuronidation, the conversion of chemical compounds to glucuronides, is a method that animals use to assist in the excretion of toxic substances, drugs or other substances that cannot be used as an energy source. Glucuronic acid is…
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Mithridatism
Mithridatism is the practice of protecting oneself against a poison by gradually self-administering non-lethal amounts. The word is derived from Mithridates VI, the King of Pontus, who so feared being poisoned that he regularly ingested small doses, aiming to develop immunity. Not to be confused with Mithraism. Background Mithridates VI‘s father, Mithridates V, was assassinated by poisoning by a conspiracy among his attendants. After…
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Dicoumarol (Moldy Sweet Clover) Toxicosis in a Group of Holstein Calves
Yamini B, Poppenga RH, Emmett BW, Judge LJ. Dicoumarol (Moldy Sweet Clover) Toxicosis in a Group of Holstein Calves. Journal of Veterinary Diagnostic Investigation. 1995;7(3):420-422. doi:10.1177/104063879500700328 References 1. Alstad AD, Casper HH, Johnson LJ: 1985, Vitamin K treatment of sweet clover poisoning in calves. J Am Vet Med Assoc 187:729–731. 2. Blakley BR: 1985, Moldy sweet clover (dicoumarol) poisoning in…
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Triiodothyronine, aka T3
Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate. Bowen, R. (2010-07-24). “Physiologic Effects of Thyroid Hormones”. Colorado State University. Retrieved 2013-09-29. Production of T3 and its prohormone thyroxine (T4) is activated by thyroid-stimulating hormone (TSH), which is released from the anterior pituitary gland. This pathway is part of a closed-loop feedback process: Elevated…
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