Tag: Venom
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Snake Venom: A Timeless Fascination
The history of humans studying snake venom is as fascinating as the venom itself, stretching back thousands of years. Let’s take a journey through time to explore how venom has captivated and terrified humanity, and how our understanding has evolved. Ancient Beginnings: Venom as Weapon and Medicine Humans have been aware of venom’s power since…
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Snake venom can have significant effects on fat distribution and adipose tissue
Stimulation of adipose tissue cells: Bothrops moojeni snake venom (Bmv) has been shown to stimulate preadipocytes, which are precursor cells to fat cells. This stimulation leads to the release of inflammatory mediators such as PGE2, IL-6, and KC/IL-8. Increased lipid accumulation: Bmv has been observed to increase lipid accumulation in preadipocytes, suggesting that it can…
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Snake Venom: The Hormone Hijacker 🐍
Imagine a villainous mastermind that can infiltrate your body’s hormonal headquarters, manipulating the delicate balance of estrogen and other hormones. Welcome to the world of snake venom, where the stakes are high and the effects are unpredictable. Estrogen’s Uninvited Guest: When Snake Venom Crashes the Hormone Hoedown Prepare for the most bizarre gatecrasher at the…
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envenomation during pregnancy is associated with increased risks including miscarriage
Several studies and case reports indicate that snake envenomation during pregnancy is associated with an increased risk of adverse outcomes, including miscarriage: Spontaneous abortions: Multiple studies report high rates of spontaneous abortions following venomous snake bites in pregnant women. One study found that nearly 30% of envenomated pregnant mothers experienced a spontaneous abortion. Fetal loss:…
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intriguing similarities between blood clotting issues associated with birth control and those caused by venomous snake bites
Estrogen effects: Birth control pills containing estrogen can increase blood clotting factors, potentially leading to an increased risk of blood clots. Similarly, some snake venoms contain components that can activate the blood clotting system. Dual mechanisms: Both birth control and certain snake venoms can affect blood clotting in opposing ways: Birth control can increase clotting risk,…
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recent breakthrough using ai to design proteins that can neutralize lethal snake venom toxins
This development, published in Nature on January 15, 2025, represents a significant advancement in snakebite treatment. Key highlights of this breakthrough include: –AI-designed proteins protected mice against lethal doses of snake toxins, achieving an 80-100% survival rate. –The new approach targets three-finger toxins (3FTxs), which are often resistant to traditional antivenoms. –These synthetic antivenoms can…
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ADAM36: The Reproductive Enigma
ADAM36 is the protein that’s playing a mysterious role in the world of reproduction! ADAM36 is like that enigmatic character in a novel who appears briefly but leaves a lasting impression. This protein is primarily expressed in the male reproductive system, particularly in the testis and epididymis. Picture ADAM36 as the secret agent of sperm…
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ADAM35: The Phantom Protein
ADAM35 is the protein that’s playing hide-and-seek with scientists! ADAM35 is like that elusive celebrity who everyone’s heard of but no one’s actually seen. This protein is shrouded in mystery, with researchers still debating its very existence in humans. Picture ADAM35 as the Bigfoot of the protein world. While it may have been spotted in…
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ADAM27: The Redundant Reproductive Regulator
ADAM27 is the protein that’s playing a subtle yet intriguing role in the world of reproduction! ADAM27 is like that understudy who’s always ready to step in but rarely gets called onto the stage. This protein is exclusively expressed in the testis, suggesting it’s got some reproductive business to attend to1. Picture ADAM27 as the…
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ADAM26: The Sperm’s Surface Specialist
ADAM26 is the protein that’s making waves on the surface of sperm! ADAM26 is like that friend who’s always on the front lines, ensuring everything runs smoothly. This protein is specifically expressed on the surface of sperm, where it plays a crucial role in sperm-egg interactions. Picture ADAM26 as the matchmaker of the reproductive world.…
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ADAM25: The Testicular Troublemaker
ADAM25 is the protein that’s making waves in the world of male reproduction! ADAM25, also known as testase 2, is like that friend who only shows up for guy’s night out. This protein is exclusively expressed in the testes, suggesting it’s got some serious business to attend to in the male reproductive system1. Picture ADAM25…
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ADAM23: The Neural Navigator
ADAM23 is the protein that’s making waves in the world of neuroscience. ADAM23 is like that friend who’s always helping you find your way around a new city. This protein is highly expressed in the central nervous system and plays a crucial role in brain development1. Picture ADAM23 as the traffic controller of the neural…
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ADAM22: The Brain’s Gatekeeper
ADAM22 is a unique member of the ADAM family, primarily expressed in the brain. Unlike many of its relatives, ADAM22 is a non-catalytic metalloprotease-like protein, meaning it lacks proteolytic activity4. Picture ADAM22 as the bouncer at an exclusive neural nightclub. It’s involved in regulating cell adhesion and spreading, and it even plays a role in…
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ADAM8: The Inflammatory Instigator
ADAM8 is the protein that’s stirring up trouble in your immune system! ADAM8 is like that friend who always shows up when there’s drama brewing. This protein is primarily expressed in immune cells, making it a key player in inflammatory responses. Picture ADAM8 as the bouncer of the cellular world. It’s involved in cell adhesion…
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ADAM31: The Elusive Rodent Relative
ADAM31 is the protein that’s playing hide-and-seek with human geneticists! ADAM31 is like that distant cousin who only shows up at family reunions in other countries. While it’s a well-known member of the ADAM family in mice, it’s conspicuously absent from the human genome. In mice, ADAM31 is expressed in the testis, suggesting a role…
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ADAM34: the Bigfoot of the protein world
Prepare to be mystified by ADAM34, the protein that’s playing an elaborate game of hide-and-seek with scientists! ADAM34 is like that elusive celebrity who everyone’s heard of, but no one’s actually seen. This protein is shrouded in mystery, with researchers still debating its very existence in humans. It’s been spotted in mice, where it’s thought…
NOTES
- 🧬 Disease Table with Low Sodium Connection
- 🧂 Sodium Reduction and Sodium Replacement: A History of Reformulation and Exploding Diseases, Including Many Diseases Unheard of Before Deadly Sodium Policies
- 🧂 The DEADLY 1500 mg Sodium Recommendation predates the WHO’s formal global sodium reduction push by nearly a decade (and it’s even worse than that)
- 🧬 What Is Beta-Glucuronidase?
- When Sugar Was Salt: Crystalline Confusion and the Covenant of Sweetness
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