Pomacea maculata perivitellin-1 (PmPV1) is a glyco-lipo-caroteno protein
Pomacea maculata perivitellin-1 (PmPV1) is the most abundant perivitellin found in the perivitelline fluid from Pomacea maculata snail eggs. This glyco-lipo-caroteno protein is an approx. 294 kDa multimer of a combination of multiple copies of six different ~30 kDa subunits. PmPV1 account >60% of the total proteins found in the Pomacea maculata eggs.
- Pasquevich MY, Dreon MS, Heras H (March 2014). “The major egg reserve protein from the invasive apple snail Pomacea maculata is a complex carotenoprotein related to those of Pomacea canaliculata and Pomacea scalaris”. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 169: 63–71. doi:10.1016/j.cbpb.2013.11.008. hdl:11336/100510. PMID 24291422.
- Giglio ML, Ituarte S, Pasquevich MY, Heras H (2016-09-12). “The eggs of the apple snail Pomacea maculata are defended by indigestible polysaccharides and toxic proteins”. Canadian Journal of Zoology. 94 (11): 777–785. doi:10.1139/cjz-2016-0049. hdl:1807/74381. ISSN 0008-4301.
PmPV1 is an orthologous of ovorubin and scalarin, sharing most of the structural features with the former protein and cross-reacting with anti-ovorubin polyclonal antibodies. Like ovorubin and scalarin, PmPV1 is highly glycosylated (~13% w/w) and carries carotenoid pigments, indicating that this perivitellin would probably have the antioxidant, photoprotective, aposematic and water retention functions described for its orthologous.
- Pasquevich MY, Dreon MS, Heras H (March 2014). “The major egg reserve protein from the invasive apple snail Pomacea maculata is a complex carotenoprotein related to those of Pomacea canaliculata and Pomacea scalaris”. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 169: 63–71. doi:10.1016/j.cbpb.2013.11.008. hdl:11336/100510. PMID 24291422.
PmPV1 is a kinetically stable protein that, like most other studied perivitellins from Pomacea snails, is highly stable in a wide range of pH values and withstands gastrointestinal digestion, characteristics associated with an antinutritive defense system that deters predation by lowering the nutritional value of the eggs. Remarkably, and in agreement with this antinutritive activity, PmPV1 withstands in vivo digestion, being recovered structurally unaltered from mice feces after trespassing the whole digestive system.
- Pasquevich MY, Dreon MS, Qiu JW, Mu H, Heras H (November 2017). “Convergent evolution of plant and animal embryo defences by hyperstable non-digestible storage proteins”. Scientific Reports. 7 (1): 15848. Bibcode:2017NatSR…715848P. doi:10.1038/s41598-017-16185-9. PMC 5696525. PMID 29158565.
References
- Pasquevich MY, Dreon MS, Heras H (March 2014). “The major egg reserve protein from the invasive apple snail Pomacea maculata is a complex carotenoprotein related to those of Pomacea canaliculata and Pomacea scalaris”. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 169: 63–71. doi:10.1016/j.cbpb.2013.11.008. hdl:11336/100510. PMID 24291422.
- Giglio ML, Ituarte S, Pasquevich MY, Heras H (2016-09-12). “The eggs of the apple snail Pomacea maculata are defended by indigestible polysaccharides and toxic proteins”. Canadian Journal of Zoology. 94 (11): 777–785. doi:10.1139/cjz-2016-0049. hdl:1807/74381. ISSN 0008-4301.
- Pasquevich MY, Dreon MS, Qiu JW, Mu H, Heras H (November 2017). “Convergent evolution of plant and animal embryo defences by hyperstable non-digestible storage proteins”. Scientific Reports. 7 (1): 15848. Bibcode:2017NatSR…715848P. doi:10.1038/s41598-017-16185-9. PMC 5696525. PMID 29158565.
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