Category: Cholecystokinin
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Kynureninase or L-Kynurenine hydrolase (KYNU) is part of the pathway for the catabolism of Trp and the biosynthesis of NAD cofactors from tryptophan (Trp).
Kynureninase or L-Kynurenine hydrolase (KYNU) (EC 3.7.1.3) is a PLP dependent enzyme that catalyses the cleavage of kynurenine (Kyn) into anthranilic acid (Ant). It can also act on 3-hydroxykynurenine (to produce 3-hydroxyanthranilate) and some other (3-arylcarbonyl)-alanines. Note: 3-Hydroxykynurenine is a metabolite of tryptophan, which filters UV light in the human lens. It is one of two pigments identified as responsible for the goldenrod crab spider‘s (Misumena vatia) yellow coloration. 3-Hydroxyanthranilic acid is an intermediate in the metabolism of tryptophan. It…
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Cholecystokinin aka pancreozymin notes
History Structure Function Gastrointestinal Digestion Satiety The effects of CCK vary between individuals. For example, in rats , CCK administration significantly reduces hunger in adult males, but is slightly less effective in younger subjects, and even slightly less effective in females. The hunger-suppressive effects of CCK also are reduced in obese rats. Fink H, Rex A, Voits M, Voigt…
