Bacterial Toxins
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Flacherie (and a ridiculous history of Bt development…roundabout)
History of Bt Development as told in New Innovative Pesticides: An Evaluation of Incentives and Disincentives for Commercial Development by Industry, Stanford Research Institute (Final Report dated September 1977, Prepared… Read more.
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Bacillus thuringiensis: the James Bond of biological pest control
In the microscopic world of bacteria, Bacillus thuringiensis (Bt), a gram-positive, soil-dwelling microbe is the go-to secret agent for farmers and gardeners worldwide, thanks to its uncanny ability to produce… Read more.
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Delta endotoxins聽(未-endotoxins) are聽pore-forming toxins聽produced by聽Bacillus thuringiensis聽species of bacteria. They are useful for their聽insecticidal聽action and are the primary toxin produced by聽Bt maize/corn.
Bt maize/Bt corn聽is a variant of聽maize聽that has been聽genetically altered聽to express one or more聽proteins聽from the聽bacteriumBacillus thuringiensis聽including聽Delta endotoxins. During聽spore聽formation the bacteria produce crystals of such proteins (hence the name聽Cry聽toxins) that are also… Read more.
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Ovalbumin
Ovalbumin聽(abbreviated聽OVA) is the main聽protein聽found in聽egg white, making up approximately 55% of the total protein.聽Ovalbumin displays sequence and three-dimensional聽homology聽to the聽serpin聽superfamily, but unlike most serpins it is not a聽serine protease聽inhibitor.聽The function of… Read more.
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Tobacco-derived 4R-cembranoid confers neuroprotection against LPS-induced hippocampal inflammation in mice (decreases levels of pro-inflammatory cytokines; improves memory function; activates STAT3, Akt1, and CREB phosphorylation; and upregulates the mRNA levels of ORM2, GDNF, and C3) independent of the 伪7 nicotinic receptor
Rojas-Col贸n, L.A., Dash, P.K., Morales-V铆as, F.A.聽et al.聽4R-cembranoid confers neuroprotection against LPS-induced hippocampal inflammation in mice.聽J Neuroinflammation聽18, 95 (2021). https://doi.org/10.1186/s12974-021-02136-9 LPS: Lipopolysaccharide “4R protects the hippocampus against inflammation and memory impairments… Read more.
