Human Clusters of Differentiation (or CD) Molecules
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Indoleamine-pyrrole 2,3-dioxygenase聽(IDO聽or聽INDO) is involved in tryptophan聽metabolism
Indoleamine-pyrrole 2,3-dioxygenase (IDO or INDO EC 1.13.11.52) is a heme-containing enzyme physiologically expressed in a number of tissues and cells, such as the small intestine, lungs, female genital tract or placenta. In humans is encoded by the IDO1 gene. IDO is involved in tryptophan metabolism. It… Read more.
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Interleukin-2-recptor alpha chain (IL2RA also called CD25) is the human protein encoded by the IL2RA gene.
The聽interleukin 2聽(IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while… Read more.
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Cluster of Differentiation (Cluster of Designation or Classification Determinant)
The聽cluster of differentiation聽(also known as聽cluster of designation聽or聽classification determinant聽and often abbreviated as聽CD) is a protocol used for the identification and investigation of聽cell surface molecules聽providing targets for聽immunophenotyping聽of cells.[1]聽In terms of physiology, CD… Read more.
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CD45antigen (Protein tyrosine phosphatase, receptor type, C聽also known as聽PTPRC and formerly known as leukocyte common antigen LCA)
Protein tyrosine phosphatase, receptor type, C also known as PTPRC is an enzyme that, in humans, is encoded by the PTPRCgene.[5] PTPRC is also known as CD45antigen (CD stands for cluster of differentiation), which was originally called leukocyte common antigen (LCA).[6] Function… Read more.
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T helper cells聽(Th cells), also known as聽CD4+聽cells聽or聽CD4-positive cells
The聽T helper cells聽(Th聽cells), also known as聽CD4+聽cells聽or聽CD4-positive cells, are a type of聽T cell聽that play an important role in the聽adaptive immune system. They aid the activity of other immune cells by releasing聽cytokines.… Read more.
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CD4
In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). CD4 is found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. It was discovered in… Read more.
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CD31
Platelet endothelial cell adhesion molecule聽(PECAM-1) also known as聽cluster of differentiation 31聽(CD31) is a聽protein聽that in humans is encoded by the聽PECAM1gene聽found on聽chromosome17q23.3.[5][6][7][8]聽PECAM-1 plays a key role in removing aged neutrophils from the… Read more.
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KIT (gene)
Proto-oncogene c-KIT聽is the gene encoding the聽receptor tyrosine kinase聽protein known as聽tyrosine-protein kinase KIT,聽CD117聽(cluster of differentiation聽117) or聽mast/stem cell growth factor receptor聽(SCFR).[5]聽Multiple transcript variants encoding different isoforms have been found for this gene.[6][7]聽KIT… Read more.
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List of human clusters of differentiation (OR CD) MOLECULES
* = group; ** = not listed on hcdm CD1* MHC-like molecule that presents lipid molecules CD1a CD1a (Cluster of Differentiation 1a), or T-cell surface glycoprotein CD1a, is a human protein encoded by the CD1A gene. An antigen-presenting… Read more.
