Category: Wikipedia
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Anti-thymocyte globulin (ATG)
Anti-thymocyte globulin (ATG) is an infusion of horse or rabbit-derived antibodies against human T cells and their precursors (thymocytes), which is used in the prevention and treatment of acute rejection in organ transplantation and therapy of aplastic anemia due to bone marrow insufficiency. Uses Two antithymocyte globulin (ATG) agents licensed for clinical use in the United States are Thymoglobulin (rabbit ATG, rATG, Genzyme) and…
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Anti-lymphocyte globulin (ALG)
Anti-lymphocyte globulin (ALG) is an infusion of animal- antibodies against human T cells which is used in the treatment of acute rejection in organ transplantation. Its use was first reported by Thomas Starzl in 1966.[1] Its use in transplant was supplanted by thymoglobulin between 1984 and 1999.[2] It has also been used in the treatment of aplastic anemia.[3][4][5] It is less commonly used than the similar anti-thymocyte globulin (ATG), and like ATG it is…
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Microphthalmia-associated transcription factor aka class E basic helix-loop-helix protein 32 or bHLHe32
Microphthalmia-associated transcription factor also known as class E basic helix-loop-helix protein 32 or bHLHe32 is a protein that in humans is encoded by the MITF gene. AKA MITF, CMM8, MI, WS2, WS2A, bHLHe32, microphthalmia-associated transcription factor, melanogenesis associated transcription factor, COMMAD, melanocyte inducing transcription factor, MITF-A RNA expression pattern Human Mouse (ortholog) Top expressed inretinal pigment epitheliumright ventriclemyocardiumvastus lateralis muscledeltoid muscleurethrarenal medullavisceral pleurasaphenous veinsecondary oocyte Top…
