Tag: ANTIBODY
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The molecular mayhem of immunogens, haptens, carriers and adjuvants
First up, the immunogen: the molecular maestro of the immune system, orchestrating a symphony of B-cells and T-cells like a conductor with a grudge. These substances don’t just knock politely on the immune system’s door—they kick it down with the force of a battering ram. Immunogens are a subset of antigens (because “antibody-generating” wasn’t obvious enough)…
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What is Immunoprecipitation (IP)?
Immunoprecipitation (IP) is a technique used to enrich protein antigens from a complex mixture using specific antibodies. To carry out an IP, antibodies must be coupled to a solid substrate, such as agarose resin or magnetic beads, to allow for purification of the target antigens. Immunoprecipitation (IP) is the technique of precipitating a protein antigen out of solution using an antibody that…
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ANITBODY MIMETIC
A protein mimetic is a molecule such as a peptide, a modified peptide or any other molecule that biologically mimics the action or activity of some other protein. Protein mimetics are commonly used in drug design and discovery. Types of mimetics There are a number of different distinct classes of protein mimetics. Antibody mimetics are organic compounds that, like antibodies, can specifically bind antigens, but…
