Tag: Brain
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đ§ The Missing Organ: Why CF Diagrams Erase the Brain
A glyphic exposĂ© on systemic omission, terrain collapse, and the neuro-redox veil in cystic fibrosis I. Introduction: The Diagram as Doctrine Cystic fibrosis (CF) is often illustrated through colorful organ maps â lungs, pancreas, intestines, sinuses, reproductive tract. These diagrams are dense with detail, listing dozens of symptoms and complications. But one organ is conspicuously…
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What vitamin D does or doesn’t do for a body that is salt/SCNâ» deficient
Vitamin D isnât just a bone booster, itâs a metabolic amplifier, and its effects shift dramatically depending on the integrity of the terrain. In a body deficient in salt (sodium) and thiocyanate (SCNâ»), vitamin Dâs usual benefits may be blunted, misdirected, or even destabilizing. đ What Vitamin D Does in a Coherent Terrain In a…
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ADAM23: The Neural Navigator
ADAM23 is the protein that’s making waves in the world of neuroscience. ADAM23 is like that friend who’s always helping you find your way around a new city. This protein is highly expressed in the central nervous system and plays a crucial role in brain development1. Picture ADAM23 as the traffic controller of the neural…
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ADAM22: The Brain’s Gatekeeper
ADAM22 is a unique member of the ADAM family, primarily expressed in the brain. Unlike many of its relatives, ADAM22 is a non-catalytic metalloprotease-like protein, meaning it lacks proteolytic activity4. Picture ADAM22 as the bouncer at an exclusive neural nightclub. It’s involved in regulating cell adhesion and spreading, and it even plays a role in…
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ADAM21: The Neurological Ninja of Reproduction
ADAM21 is the protein that’s bridging the gap between your brain and your… well, let’s just say your reproductive ambitions! ADAM21 is like that friend who’s always making unexpected connections. While most ADAM proteins are content with hanging out in the reproductive organs, ADAM21 decided to take the scenic route through the nervous system. Picture…
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ADAM10: The Cellular Scissorhands of Reproduction
Prepare to be amazed by ADAM10, the Edward Scissorhands of the cellular world! This protein isn’t just content with the usual reproductive shenanigans; it’s got its fingers in pies all over the body. Picture ADAM10 as a molecular barber, constantly snipping and trimming proteins on cell surfaces. But unlike your average hairdresser, ADAM10 doesn’t just…
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Thecal Sac or Dural Sac
The thecal sac or dural sac is the membranous sheath (theca) or tube of dura mater that surrounds the spinal cord and the cauda equina. The thecal sac contains the cerebrospinal fluid which provides nutrients and buoyancy to the spinal cord.[1] From the skull the tube adheres to bone at the foramen magnum and extends down to the second sacral vertebra where it tapers to cover over the filum terminale. Along most of the spinal canal it is separated…
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Xylotheque
A xylotheque or xylothek (from the Greek xylon for “wood” and theque meaning “repository”) is special form of herbarium that consists of a collection of authenticated wood specimens.[1] It is also known as a xylarium (from the Greek xylon for “wood” and Latin arium meaning “separate place”). Traditionally, xylotheque specimens were in the form of book-shaped volumes, each made of a particular kind of wood and holding samples of the different parts…
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Thermolysin – The Tiny Terminator of Plasma Proteins!
Both thermolysin and snake venom metalloproteinases (SVMPs) share a similar mechanism of action, utilizing zinc ions to hydrolyze peptide bonds in proteins
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Oxytocin: The Molecular Maestro of Love and Labor
Buckle up, hormone enthusiasts! We’re about to take a wild ride into the world of oxytocin, the “love hormone” that’s been playing Cupid in our bodies since the dawn of mammalian evolution. This tiny peptide packs a punch that would make even Hercules jealous! Picture this: a molecule barely 1007 Da in size, strutting around…
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Benjamin Rush: The Founding Father of American Psychiatry
Benjamin Rush (1746-1813) wasn’t just a signer of the Declaration of Independence; he was also a pioneering physician who laid the groundwork for modern psychiatry in America. Born near Philadelphia to Quaker parents, Rush received his medical degree from the University of Edinburgh in 1768 before returning to Philadelphia to establish his practice. As a civic…
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Johann Christian Reil: The Mad Genius Who Coined “Psychiatry”
Johann Christian Reil (1759â1813) wasnât your average 18th-century doctor. He was the kind of guy who looked at the chaos of the human mind and thought, âYou know what this needs? A whole new field of medicine.â And so, in 1808, he coined the term âpsychiatryââa word derived from the Greek psyche (soul) and iatreia (healing), meaning âthe healing…
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Thorazine: chemical straitjacket
This is the absolutely bonkers tale of Thorazine, the wonder drug that turned mental hospitals into zombie discos! Picture this: It’s the 1950s, and French scientists are busy cooking up antihistamines like they’re trying to win a sneezing contest. But oops! They accidentally create a drug that makes people act like they’ve had a lobotomy…
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The Merry-go-round from hell for the mentally unstable
Picture this: It’s 1810, and ol’ Benny Rush, fresh off his success with the Tranquilizing Chair, thinks to himself, “You know what would really cure madness? A merry-go-round from hell!” Enter the Gyrator, a centrifugal spinning board designed to improve circulation to the brain. Because nothing says “mental health” like being strapped to a giant,…
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Steroidogenic factor 1Â (SF-1)Â protein and a few related things
The steroidogenic factor 1 (SF-1) protein is a transcription factor involved in sex determination by controlling the activity of genes related to the reproductive glands or gonads and adrenal glands. This protein is encoded by the NR5A1 gene, a member of the nuclear receptor subfamily, located on the long arm of chromosome 9 at position 33.3. It was originally identified as a regulator of genes encoding cytochrome P450 steroid hydroxylases, however, further roles…
