Tag: Fibrosis
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🦴 Joint Disorders and the Ionic Collapse
Joint pain and degeneration are often framed as mechanical or autoimmune problems. But mounting evidence suggests that chronic joint disorders are also failures of immune coordination, vascular repair, and connective tissue signaling—all of which are governed by the PF4–CXCR4–CXCL12 axis and deeply influenced by ionic balance, especially sodium. 🔹 1. The PF4–CXCR4–CXCL12 Axis in Joint…
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HFE H63D & VO2Â max
SMOKE EM IF YOU GOT EM The HFE H63D is a single-nucleotide polymorphism in the HFE gene (c.187C>G, rs1799945), which results in the substitution of a histidine for an aspartic acid at amino acid position 63 of the HFE protein (p.His63Asp). HFE participates in the regulation of iron absorption. Homozygous H63D variant can occasionally be the cause of hemochromatosis. It is also…
NOTES
- 🧬 Disease Table with Low Sodium Connection
- 🧂 Sodium Reduction and Sodium Replacement: A History of Reformulation and Exploding Diseases, Including Many Diseases Unheard of Before Deadly Sodium Policies
- 🧂 The DEADLY 1500 mg Sodium Recommendation predates the WHO’s formal global sodium reduction push by nearly a decade (and it’s even worse than that)
- 🧬 What Is Beta-Glucuronidase?
- When Sugar Was Salt: Crystalline Confusion and the Covenant of Sweetness
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